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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">dan</journal-id><journal-title-group><journal-title xml:lang="ru">Доклады Национальной академии наук Беларуси</journal-title><trans-title-group xml:lang="en"><trans-title>Doklady of the National Academy of Sciences of Belarus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-8323</issn><issn pub-type="epub">2524-2431</issn><publisher><publisher-name>The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29235/1561-8323-2018-62-6-719-724</article-id><article-id custom-type="elpub" pub-id-type="custom">dan-572</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MEDICINE</subject></subj-group></article-categories><title-group><article-title>Новый подход к лечению хронических дистрофических заболеваний роговицы</article-title><trans-title-group xml:lang="en"><trans-title>New approach to treating chronic dystrophic cornea diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семак</surname><given-names>Г. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Semak</surname><given-names>G. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><bio xml:lang="en"><p>Ph. D. (Medicine), Associate professor</p></bio><email xlink:type="simple">semakgalina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Людчик</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyudchik</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">sermaxse@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жерко</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zherko</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студент</p></bio><bio xml:lang="en"><p>Student</p></bio><email xlink:type="simple">zherko.irina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Белорусский государственный медицинский университет, Минск</institution></aff><aff xml:lang="en"><institution>Belarusian State Medical University, Minsk</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>13</day><month>01</month><year>2019</year></pub-date><volume>62</volume><issue>6</issue><fpage>719</fpage><lpage>724</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семак Г.Р., Людчик А.В., Жерко И.Ю., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Семак Г.Р., Людчик А.В., Жерко И.Ю.</copyright-holder><copyright-holder xml:lang="en">Semak G.R., Lyudchik A.V., Zherko I.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://doklady.belnauka.by/jour/article/view/572">https://doklady.belnauka.by/jour/article/view/572</self-uri><abstract><p>В группе пациентов с хроническими дистрофическими заболеваниями роговицы была исследована эффективность коррекции болезни сухого глаза методом субконъюнктивального введения 1 %-ного натрия гиалуроната. Описаны функции гиалуроновой кислоты в зависимости от ее молекулярной массы. Проведенные исследования показывают необходимость использования инъекционной формы гиалуроната натрия при лечении пациентов с заболеванием глазной поверхности.</p></abstract><trans-abstract xml:lang="en"><p>The efficiency of the treatment of dry eye disease patients with keratopathy at a subconjunctival injection of 1 % sodium hyaluronate was studied. This review describes the functions of hyaluronic acid depending on its molecular weight. The performed study shows the necessity of using the injection form of sodium hyaluronate in the treatment of patients with dry eye disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гиалуроновая кислота</kwd><kwd>болезнь сухого глаза</kwd><kwd>регенерация</kwd><kwd>дистрофии роговицы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hyaluronic acid</kwd><kwd>dry eye disease</kwd><kwd>regeneration</kwd><kwd>corneal dystrophy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">TFoS DEWS II Introduction // The ocular Surface. 2017 [Electronic resource]. – Mode access: http://www. theocularsurfacejournal.com/article/S1542. – Date access: 20.07.2017.</mixed-citation><mixed-citation xml:lang="en">TFoS DEWS II Introduction. The Ocular Surface. 2017. Available at: http://www.theocularsurfacejournal.com/article/ S1542 (accessed 20 July 2018).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Eﬀect of hyaluronic acid on tear ﬁlm thickness as assessed with ultra-high resolution optical coherence tomography / S. kaya [et al.] // Acta ophthalmol. – 2015. – Vol. 93, N 5. – P. 439–443. https://doi.org/10.1111/aos.12647</mixed-citation><mixed-citation xml:lang="en">kaya S., Schmidl D., Schmetterer l., Witkowska k. J., Unterhuber A., Aranha dos Santos V., Baar C., Garhöfer G., Werkmeister R. M. Eﬀect of hyaluronic acid on tear ﬁlm thickness as assessed with ultra-high resolution optical coherence tomography. Acta Ophthalmologica, 2015, vol. 93, no. 5, pp. 439–443. https://doi.org/10.1111/aos.12647</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">HyAl1 hyaluronidase in prostate cancer: a tumor promoter and suppressor / V. B. lokeshwar [et al.] // Cancer Res. – 2005. – Vol. 65, N 17. – P. 7782–7789. https://doi.org/10.1158/0008-5472.can-05-1022</mixed-citation><mixed-citation xml:lang="en">lokeshwar V. B., Cerwinka W. H., Isoyama T., lokeshwar B. l. HyAl1 hyaluronidase in prostate cancer: a tumor promoter and suppressor. Cancer Research, 2005, vol. 65, no. 17, pp. 7782–7789. https://doi.org/10.1158/0008-5472.can-05-1022</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">oligosaccharides of hyaluronan are potent activators of dendritic cells / C. C. Termeer [et al.] // J. Immunol. – 2000. – Vol. 165, N 4. – P. 1863–1870. https://doi.org/10.4049/jimmunol.165.4.1863</mixed-citation><mixed-citation xml:lang="en">Termeer C. C., Hennies J., Voith U., Ahrens T., Weiss J. M., Prehm P., Simon J. C. oligosaccharides of hyaluronan are potent activators of dendritic cells. Journal of Immunology, 2000, vol. 165, no. 4, pp. 1863–1870. https://doi.org/10.4049/ jimmunol.165.4.1863</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Simpson, M. A. Hyaluronan and hyaluronidase in genitourinary tumors / M. A. Simpson, V. B. lokeshwar // Front. Biosci. – 2008. – Vol. 13. – P. 5664–5680. https://doi.org/10.2741/3108</mixed-citation><mixed-citation xml:lang="en">Simpson M. A., lokeshwar V. B. Hyaluronan and hyaluronidase in genitourinary tumors. Frontiers in Bioscience, 2008, vol. 13, pp. 5664–5680. https://doi.org/10.2741/3108</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
