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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">dan</journal-id><journal-title-group><journal-title xml:lang="ru">Доклады Национальной академии наук Беларуси</journal-title><trans-title-group xml:lang="en"><trans-title>Doklady of the National Academy of Sciences of Belarus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-8323</issn><issn pub-type="epub">2524-2431</issn><publisher><publisher-name>The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29235/1561-8323-2019-63-3-343-349</article-id><article-id custom-type="elpub" pub-id-type="custom">dan-621</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MEDICINE</subject></subj-group></article-categories><title-group><article-title>Иммуногистохимические доказательства эффективности гиалуроновой кислоты в лечении кератопатий</article-title><trans-title-group xml:lang="en"><trans-title>Immunohistochemical proofs of the efficiency of hyaluronic acid in keratopathy treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семак</surname><given-names>Г. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Semak</surname><given-names>G. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семак Галина Романовна – канд. мед. наук, доцент</p><p>пр. Дзержинского, 83, 220116, Минск, Республика Беларусь</p></bio><bio xml:lang="en"><p>Semak Galina Romanovna – Ph. D. (Medicine), Associate professor</p><p>83, Dzerzhinsky Ave., 220116, Minsk, Republic of Belarus</p></bio><email xlink:type="simple">semakgalina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захарова Виктория Алексеевна – канд. мед. наук, доцент</p><p>пр. Дзержинского, 83, 220116, Минск, Республика Беларусь</p></bio><bio xml:lang="en"><p>Zaharova Viktoriya Alekseevna – Ph. D. (Medicine), Associate professor</p><p>83, Dzerzhinsky Ave., 220116, Minsk, Republic of Belarus</p></bio><email xlink:type="simple">zakharava.vikt@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клецкий</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kletsky</surname><given-names>S. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клецкий Семён Кивович – канд. мед. наук, доцент</p><p>пр. Дзержинского, 83, 220116, Минск, Республика Беларусь</p></bio><bio xml:lang="en"><p>Kletsky Semen Kivovich – Ph. D. (Medicine), Associate professor</p><p>83, Dzerzhinsky Ave., 220116, Minsk, Republic of Belarus</p></bio><email xlink:type="simple">s.kletski@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Летковская</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Letkovskaya</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Летковская Татьяна Анатольевна – канд. мед. наук, доцент</p><p>пр. Дзержинского, 83, 220116, Минск, Республика Беларусь</p></bio><bio xml:lang="en"><p>Letkovskaya Tatiana Anatolievna – Ph. D. (Medicine), Associate professor</p><p>83, Dzerzhinsky Ave., 220116, Minsk, Republic of Belarus</p></bio><email xlink:type="simple">taletkovskaya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жерко</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zherko</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жерко Ирина Юрьевна – студент</p><p>пр. Дзержинского, 83, 220116, Минск, Республика Беларусь</p></bio><bio xml:lang="en"><p>Zherko Irina Yurievna – Student</p><p>83, Dzerzhinsky Ave., 220116, Minsk, Republic of Belarus</p></bio><email xlink:type="simple">zherko.irina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Белорусский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Belarusian State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>27</day><month>06</month><year>2019</year></pub-date><volume>63</volume><issue>3</issue><fpage>343</fpage><lpage>349</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семак Г.Р., Захарова В.А., Клецкий С.К., Летковская Т.А., Жерко И.Ю., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Семак Г.Р., Захарова В.А., Клецкий С.К., Летковская Т.А., Жерко И.Ю.</copyright-holder><copyright-holder xml:lang="en">Semak G.R., Zakharova V.A., Kletsky S.K., Letkovskaya T.A., Zherko I.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://doklady.belnauka.by/jour/article/view/621">https://doklady.belnauka.by/jour/article/view/621</self-uri><abstract><p>Представлен анализ изменений экспрессии CD44 и MMP9 на фоне терапии кератопатий в исходе воспалительных заболеваний роговицы c использованием инъекционной формы гиалуроновой кислоты.</p></abstract><trans-abstract xml:lang="en"><p>An analysis of changes in the CD44 and MMP9 expression during the keratopathy after corneal inflammatory diseases treatment with injected hyaluronic acid is presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гиалуроновая кислота</kwd><kwd>регенерация</kwd><kwd>дистрофии роговицы</kwd><kwd>иммуногистохимия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hyaluronic acid</kwd><kwd>dry eye disease</kwd><kwd>regeneration</kwd><kwd>corneal dystrophy</kwd><kwd>immunohistochemistry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ezra, D. 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