Elastification of the arterial wall by high-intensity low-frequency ultrasound
https://doi.org/10.29235/1561-8323-2023-67-4-287-294
Abstract
A significant increase in the elasticity of the femoropopliteal artery segments in vitro was found as a result of the action of cavitation generated by powerful low-frequency (24–26 kHz) ultrasound introduced into the vessel by a flexible waveguide. The vessel elasticity was evaluated both by the deflection under the action of an external force and by the degree of its expansion vasodilatation by the internal pressure created by the expanding balloon. The possibility of achieving a more than two-fold decrease in the vascular wall elasticity modulus after 30-s exposure to an ultrasound intensity of 31 W/cm2 was shown. It has been established that at the 10 μm amplitude of ultrasonic vibrations, vascular wall damage occurs in the form of small foci of detachment and rupture of the intima accompanied by delamination in the media layer, when polymorphic slit-like cavities are formed with an increase in the amplitude of oscillations above 23 μm.
Supporting agencies: The work was supported by the Belarusian Republican Foundation for Fundamental Research (Grant M21-004)
About the Authors
I. E. Adzerikho
Belarusian Medical Academy of Postgraduate Education
Belarus
Belarus
Adzerikho Igor E. – D. Sc. (Medicine), Professor
3/3, P. Brovka Str., 220013, Minsk
A. I. Kulak
Institute of General and Inorganic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Kulak Anatoly I. – Academician, D. Sc. (Chemistry), Professor, Director. Institute of General and Inorganic Chemistry of the National Academy of Sciences of Belarus (
9/1, Surganov Str., 220072, Minsk
T. E. Vladimirskaya
Belarusian Medical Academy of Postgraduate Education
Belarus
Belarus
Vladimirskaya Tatyana E. – Ph. D. (Biology)
3/3, P. Brovka Str., 220013, Minsk
T. V. Leonchik
Belarusian Medical Academy of Postgraduate Education
Belarus
Belarus
Leonchik Ekaterina V. – Junior Researcher
3/3, P. Brovka Str., 220013, Minsk
S. N. Chur
Belarusian State Medical University
Belarus
Belarus
Chur Sergey N. – Ph. D. (Medicine), Associate Professor
83, Dzerzhinsky Ave., 220083, Minsk
V. T. Minchenya
Scientific and Technological Park of the Belarusian National Technical University “Polytechnic”
Belarus
Belarus
Minchenya Vladimir T. – Ph. D. (Engineering), Associate Professor
24, Y. Kolas Str., 220013, Minsk
S. V. Shil’ko
V. A. Bely Metal-Polymer Research Institute of the National Academy of Sciences of Belarus
Belarus
Belarus
Shil’ko Sergei V. – Ph. D. (Engineering), Associate Professor
32a, Kirov Str., 246050, Gomel
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