ENHANCE MENT OF THE EFFICIENCY OF CYTOLOGICAL DIAGNOSIS OF CHRONIC PANCREATITIS AND PANCREATIC ADENOCARCINOMA BY AN EXPERT SYSTEM
Abstract
Using the karyometry method, quantitative regularities of pathological changes in nuclei of cells of ductal epithelium of pancreas in adenocarcinoma and chronic pancreatitis were revealed. The expert system for diagnosis of these diseases on the basis of a set of threshold values of quantitative parameters of nuclei in the comparison groups and their weight coefficients has been created. The efficiency of the expert system in the preoperative diagnosis of adenocarcinoma and chronic pancreatitis was 100 % and its substantial contribution to the clarification of the diagnosis in the cases with the cytologic conclusion as "suspicion of cancer! was estimated.
About the Authors
V. A. KIRILLOV
Belarusian State Medical University, Minsk
Belarus
Belarus
K. A. LUHAVETS
International State Environmental Institute named A. D. Sakharov by Belarusian State University, Minsk
Belarus
Belarus
O. A. EROKHINA
N. N. Alexandrov National Cancer Centre of Belarus, Minsk
Belarus
Belarus
L. B. KLIUKINA
N. N. Alexandrov National Cancer Centre of Belarus, Minsk
Belarus
Belarus
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