PROGNOSTIC FACTORS IN THE TREATMENT OF BREAST CANCER
Abstract
It was shown that the butyrylcholinesterase activity in the blood of women with non-malignant breast cancer was lower as compared to patients with malignant breast cancer (P < 0,001). Using two dimensional gel-electrophoresis method it was found that blood plasma proteomic maps are different for patients with various molecular subtypes of breast cancer. Identified differences consist in the appearance of additional new proteins and changes in the expression of proteins present in norm. Current data provide an advance to develop supplemental methods of breast cancer diagnosis and prognosis of the therapy outcomes.
About the Authors
N. A. SHUKANOVA
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
L. V. DUBOVSKAYA
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
Y. S. BAKAKINA
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
M. A. MARTYNOVA
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
N. A. KAZLOUSKAYA
N. N. Alexandrov National Cancer Centre of Belarus
Belarus
Belarus
E. V. SHAPOVAL
N. N. Alexandrov National Cancer Centre of Belarus
Belarus
Belarus
I. M. BUSHMAKINA
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
M. M. MOLCHAN
Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus
Belarus
Belarus
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