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New approach to treating chronic dystrophic cornea diseases

https://doi.org/10.29235/1561-8323-2018-62-6-719-724

Abstract

The efficiency of the treatment of dry eye disease patients with keratopathy at a subconjunctival injection of 1 % sodium hyaluronate was studied. This review describes the functions of hyaluronic acid depending on its molecular weight. The performed study shows the necessity of using the injection form of sodium hyaluronate in the treatment of patients with dry eye disease.

About the Authors

G. R. Semak
Belarusian State Medical University, Minsk
Belarus
Ph. D. (Medicine), Associate professor


A. V. Lyudchik
Belarusian State Medical University, Minsk
Belarus


I. Yu. Zherko
Belarusian State Medical University, Minsk
Belarus
Student


References

1. TFoS DEWS II Introduction. The Ocular Surface. 2017. Available at: http://www.theocularsurfacejournal.com/article/ S1542 (accessed 20 July 2018).

2. kaya S., Schmidl D., Schmetterer l., Witkowska k. J., Unterhuber A., Aranha dos Santos V., Baar C., Garhöfer G., Werkmeister R. M. Effect of hyaluronic acid on tear film thickness as assessed with ultra-high resolution optical coherence tomography. Acta Ophthalmologica, 2015, vol. 93, no. 5, pp. 439–443. https://doi.org/10.1111/aos.12647

3. lokeshwar V. B., Cerwinka W. H., Isoyama T., lokeshwar B. l. HyAl1 hyaluronidase in prostate cancer: a tumor promoter and suppressor. Cancer Research, 2005, vol. 65, no. 17, pp. 7782–7789. https://doi.org/10.1158/0008-5472.can-05-1022

4. Termeer C. C., Hennies J., Voith U., Ahrens T., Weiss J. M., Prehm P., Simon J. C. oligosaccharides of hyaluronan are potent activators of dendritic cells. Journal of Immunology, 2000, vol. 165, no. 4, pp. 1863–1870. https://doi.org/10.4049/ jimmunol.165.4.1863

5. Simpson M. A., lokeshwar V. B. Hyaluronan and hyaluronidase in genitourinary tumors. Frontiers in Bioscience, 2008, vol. 13, pp. 5664–5680. https://doi.org/10.2741/3108


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ISSN 1561-8323 (Print)
ISSN 2524-2431 (Online)