Predictive significance of a complex approach in determining the vascular wall stiffness parameters in patients with arterial hypertension and in patients with arterial hypertension after ischemic stroke
https://doi.org/10.29235/1561-8323-2022-66-5-525-532
Abstract
The article presents the information about the predictive significance of a complex approach in determining vascular wall stiffness parameters. A total of 159 people with arterial hypertension (AH) and AH after a previous ischemic stroke were examined. A model with a conditional linear predictor (LP) was constructed, using a binary regression equation with a probit-link function for prediction of cardiovascular events. LP is a combination of indicators such as age (А), glomerular filtration rate (CKD-EPI), pulse wave velocity (PWV), intima- media thickness (IMT), cardio-ankle vascular index (CAVI) and augmentation index (AI). The equation has the following form: LP = –6.6139 – 0.0978A + 0.031CKDEPI + 0.0758PWV + 3.2086IMT + 0.4421CAVI + 1.2429AI. The cut-off threshold for LP = 0.0238, sensitivity (Se) 85.71 %, specificity (Sp) 77 % and accuracy (Acc) 78.07 %.
About the Authors
V. G. Kindaliova
Grodno State Medical University
Belarus
Belarus
Kindaliova Volha G. – Ph. D. (Medicine), Senior Lecturer
80, Gorky Str., 230009, Grodno
T. P. Pronko
Grodno State Medical University
Belarus
Belarus
Pronko Tatiana P. – Ph. D. (Medicine), Associate Professor, Head of Department
80, Gorky Str., 230009, Grodno
M. A. Dobrodey
Grodno State Medical University
Belarus
Belarus
Dobrodey Maria A. – Ph. D. (Medicine), Associate Professor
80, Gorky Str., 230009, Grodno
S. V. Gubkin
Institute of Physiology of the National Academy of Sciences of Belarus
Belarus
Belarus
Gubkin Sergey V. – Corresponding Member, D. Sc. (Medicine), Professor, Director
28, Akademicheskaya Str., 220072, Minsk
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