SYNTHESIS AND STRUCTURE OF COMPLEXES OF COPPER(II) CHLORIDE AND BROMIDE WITH 4,5-DICHLOROISOTHIAZOLE-N-(2-HYDROXYETHYL)-3-CARBOXAMIDE

V. I. Potkin; A. V. Kletskov; E. V. Lider; L. G. Lavrenova; R. M. Zolotar

doi:undefined

SYNTHESIS AND STRUCTURE OF COMPLEXES OF COPPER(II) CHLORIDE AND BROMIDE WITH 4,5-DICHLOROISOTHIAZOLE-N-(2-HYDROXYETHYL)-3-CARBOXAMIDE

V. I. Potkin, A. V. Kletskov, E. V. Lider, L. G. Lavrenova, R. M. Zolotar

Full Text:

PDF (Rus) |

Generate QR code

Abstract

Copper(II) chloride and bromide complexes with 4,5-dihlorizotiazol-N-(2-hydroxyethyl)-3-carboxamide (L) with the compositions [CuLHal₂ ]_n , where Hal = Cl^– , Br^– , are synthesized. The X-ray analysis revealed that the ligand is coordinated to the copper(II) atoms tridentate by the nitrogen atom of the heterocycle and two exocyclic oxygen atoms to form polymer chains. The copper bromide complex showed a synergistic effect in the compositions of insecticides Kerber and Vitan.

Keywords

isothiazole, amide, copper(II) halide complexes, X-ray structure analysis, biological activity

References

1. Bioactive Heterocyces III / F. Clerici [et al.]. - Berlin; Heidelberg: Springer, 2007. - Vol. 9. - P. 179-220.

2. Sulphasomizole (5-p-amino-benzenesulphonamido-3-methylisothiazole): a new antibacterial sulphonamide / A. Adams [et al.] // Nature. - 1960. - Vol. 186, N 4721. - P. 221-222.

3. Ziprasidone (CP-88,059): a new antipsychotic with combined dopamine and serotonin receptor antagonist activity / T. F. Seeger [et al.] // J. Pharmacol. Exp. Ther. - 1995. - Vol. 275, N 1. - P. 101-113.

4. Isothiazolecarboxylic acid derivatives, rice blast control agents containing same as active ingredients, and rice blast control method applying control agents: pat. CN1029189C, Peop. Rep. China: IPC C07D275/02, C07D417/06, C07D275/03, A01N43/80 / K. Ishikawa, H. Tanigawa, H. Kawashima, Y. Kanemoto, H. Shimotori, J. Yanase, T. Sekino, N. Tomura, T. Kuwazuka; publ. date 05.07.1995.

5. Onrust, S. V. Perospirone / S. V. Onrust, K. McClellan // CNS Drugs. - 2001. - Vol. 15, N 4. - P. 329-337.

6. Farrell, N. Transition Metal Complexes as Drugs and Chemotherapeutic Agents / N. Farrell. - Dordrecht: Springer Netherlands, 1989. - Vol. 11. - P. 291.

7. Ronconi, L. Using coordination chemistry to design new medicines / L. Ronconi, P. J. Sadler // Coord. Chem. Rev. - 2007. - Vol. 251. - P. 1633-1648.

8. Peach, M. E. Some transition metal complexes of isothiazole / M. E. Peach, K. K. Ramaswamy // Inorganica Chim. Acta. - 1971. - Vol. 5. - P. 445-448.

9. Bumagin, N. A. Funktsionalizirovannye izoksazol'nye i izotiazol'nye ligandy: dizain, sintez, kompleksy s palladiem, gomogennyi i geterogennyi kataliz v vodnykh sredakh / N. A. Bumagin, V. I. Potkin // Izv. AN. Ser. khim. - 2016. - № 2. - S. 321-332.

10. Isoxazol-3-yl(isothiazol-3-yl)-1,2,4-triazoles, -tetrazoles, and -1,3,4-oxadiazoles: synthesis, palladium complexes, and catalytic applications / N. A. Bumagin [et al.] // Chem. Het. Comp. - 2014. - Vol. 49, N 10. - R. 1515-1529.

11. Synthesis of Novel Vanillin Derivatives Containing Isothiazole Moieties and its Synergistic Effect in Mixtures with Insecticides / V. Potkin [et al.] // Nat. Prod. Commun. - 2009. - Vol. 4, N 9. - P. 1205-1208.

12. Effekt sinergizma u proizvodnykh 4,5-dikhlorizotiazola v smesi s tsipermetrinom / A. Ya. Nikitin [i dr.] // Dezinf. delo. - 2014. - № 2. - S. 23-27.

13. Biologically active complexes of Pt(II), Pd(II), and Cu(II) with nitrogen-containing ligands / E. V. Lider [et al.] // Sviridov Readings 2015: 7th Intern. Conf. on Chemistry and Chemical Education, Minsk, Belarus, 7-11 April, 2015. Book of Abstr. - Minsk: Krasico-Print, 2015. - P. 109-110.

14. Orlin, N. A. Vliyanie ionov zheleza i medi na sostoyanie insektitsidov / N. A. Orlin // Sovremennye naukoemkie tekhnologii. - 2007. - № 12. - S. 123.

15. Sintez, struktura i magnitnye svoistva novogo kompleksa khlorida medi(II) s 3-(gidroksiiminometil)-5- (2,5-dimetilfenil)izoksazolom / O. G. Shakirova [i dr.] // Zhurn. strukt. khimii. - 2010. - T. 51, № 4. - S. 730-735.

16. Kristallicheskaya i molekulyarnaya struktura 3-trikhlormetil-4-khlor-5-izopropiloksiizotiazola i 4,5-di- khlorizotiazol-3-karbonovoi kisloty / A. I. Verenich [i dr.] // Khimiya geterotsikl. soed. - 1992. - № 3. - S. 399-402.

17. Nakamoto, K. IK spektry i spektry KR neorganicheskikh soedinenii / K. Nakamoto. - M.: Mir, 1991. - 536 s.

18. Sheldrick, G. M. A short history of SHELX / G. M. Sheldrick // Acta Crystallogr. Sect. A Found. Crystallogr. - 2008. - Vol. 64, N 1. - P. 112-122.

19. Spek, A. L. Structure validation in chemical crystallography / A. L. Spek // Acta Crystallogr. Sect. D Biol. Crystallogr. - 2009. - Vol. 65, N 2. - P. 148-155.

This work is licensed under a Creative Commons Attribution 4.0 License.

ISSN 1561-8323 (Print)
ISSN 2524-2431 (Online)

Doklady of the National Academy of Sciences of Belarus

SYNTHESIS AND STRUCTURE OF COMPLEXES OF COPPER(II) CHLORIDE AND BROMIDE WITH 4,5-DICHLOROISOTHIAZOLE-N-(2-HYDROXYETHYL)-3-CARBOXAMIDE

Full Text:

Abstract

Keywords

About the Authors

References

Review

Username
Password
	Remember me

User

Doklady of the National Academy of Sciences of Belarus

SYNTHESIS AND STRUCTURE OF COMPLEXES OF COPPER(II) CHLORIDE AND BROMIDE WITH 4,5-DICHLOROISOTHIAZOLE-N-(2-HYDROXYETHYL)-3-CARBOXAMIDE

Full Text:

Abstract

Keywords

About the Authors

References

Review

Cookies policy