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EFFECT OF LIPOSOMAL STREPTOKINASE ON THE D-DIMERS FORMATION

Abstract

Liposomal streptokinase (a mixture of free (66.3  %) and entrapped (23.7  %) drug) with a diameter of ~60 nm was prepared. The analysis of the D-dimers formation kinetics in the dog’s blood plasma showed that the liposomal streptokinase had
a prolonged effect up to 180 minutes.

About the Authors

K. I. Dubatouka
Institute of Chemistry of New Materials of the National Academy of Sciences of Belarus
Belarus
Junior researcher


V. E. Agabekov
Institute of Chemistry of New Materials of the National Academy of Sciences of Belarus
Belarus
Academician, D. Sc. (Chemistry), Professor, Director


I. L. Lutsik
Belarusian Medical Academy of Postgraduate Education
Belarus
Junior researcher


V. M. Yatsevich
Belarusian Medical Academy of Postgraduate Education
Belarus
Junior researcher


I. E. Adzerikho
Belarusian Medical Academy of Postgraduate Education
Belarus
D. Sc. (Medicine), Professor


References

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ISSN 1561-8323 (Print)
ISSN 2524-2431 (Online)