METHOD OF EVALUATION OF THE ARTERIAL VESSEL “BIOLOGICAL AGE” THROUGH THE VASCULAR WALL STIFFNESS, CONSIDERING THE DEPENDENCE OF ARTERIAL STIFFNESS ON HEART RATE AND BLOOD PRESSURE
Abstract
We have developed the method for evaluation of the arterial vessel “biological age” (BA) through arterial wall stiffness. Stiffness is determined using a new index, which is independent of blood pressure and heart rate. These features of the used index allow neutralizing the effect of blood pressure and heart rate on arterial stiffness. Therefore, the evaluation of BA based on the proposed method is reasonably accurate. It gives the possibility of a highly reliable detection of the arterial system accelerated aging. The method is implemented in detail for the common carotid artery. We have established the formulas determining its BA index through stiffness index and heart rate values.
About the Authors
E. I. Gaishun
1 Minsk City Clinical Hospital
Belarus
Ph. D. (Medicine), Head of the Department
Belarus
Ph. D. (Medicine), Head of the Department
I. V. Gaishun
Institute of Mathematics of the National Academy of Sciences of Belarus
Belarus
Academician, D. Sc. (Physics and Mathematics), Professor, Director
Belarus
Academician, D. Sc. (Physics and Mathematics), Professor, Director
A. M. Pristrom
Belarusian Medical Academy of Postgraduate Education
Belarus
D. Sc. (Medicine), Professor, Head of the Department
Belarus
D. Sc. (Medicine), Professor, Head of the Department
References
1. Plakuev A. N., Yuriev M. Yu., Yuriev Yu. Yu. Modern concepts of ageing and assessment of human biological age. Ekologiya cheloveka [Human Ecology], 2011, vol. 4, pp. 17−25 (in Russian).
2. Voitenko V. P., Tokar’ A. V., Polyukhov A. M. Methods for determination of the human biological age. Biologicheskii vozrast. Nasledstvennost’ i starenie. Gerontologiia i geriatriia [Biological age. Heredity and aging. Gerontology and geriatrics]. Kiev, 1984, pp. 133–137 (in Russian).
3. Belozerova L. M. Estimation of the biological age by means of echocardiography. Uspekhi gerontologii [Advances in Gerontology], 2006, vol. 19, pp. 90–92 (in Russian).
4. Shcherbakova A. V., Mikhalevich I. M., Barkhatova E. V., Abramovich S. G., Larionova E. M. The way of determination of biological age of the person. Patent no. 2294692 Russian Federation. Published by 10.03.2007 (in Russian).
5. Gaishun E. I., Gaishun I. V., Pristrom А. М. Method of assessment of the “biological age” of arteries as one of the factors of organism ageing. Vestsі Natsyianal’nai akademіі navuk Belarusі. Seryia medytsynskіkh navuk [Proceedings of the National Academy of Sciences of Belarus, medical series], 2016, no. 3, pp. 93–98 (in Russian).
6. Gaishun E. I., Gaishun I. V., Pristrom А. М. “Biological age” of common carotid artery in men with essential hypertension. Kardiologiia v Belarusi [Cardiology in Belarus], 2016, vol. 8, no. 4, pp. 506−511 (in Russian).
7. Gaishun E. I., Gaishun I. V., Pristrom А. М. Damping function of arteries and non-invasive methods of its assessment. Minsk, Belorusskaya nauka, 2016. 92 p. (in Russian).
8. Gaishun E. I., Gaishun I. V., Pristrom А. М. Change of the arterial distensibility depending on a 24-hour ambulatory heart rate. Doklady Natsional’noi akademii nauk Belarusi [Doklady of the National Academy of Sciences of Belarus], 2015, vol. 59, no. 3, pp. 93−96 (in Russian).
9. Pristrom А. М., Gaishun E. I. Method for diagnosis of the violation of elastic properties of the common carotid artery: instructions for use. No. 030-0313.2013 (in Russian).
10. Glantz S. Primer of Biostatistics. New York, McGraw-Hill, 1994. 489 p.
Review
Views: 680
Email this article 