lipid composition of blood plasma high density lipoproteins as marker of metabolic reactions of urgent adaptations under acute stress
https://doi.org/10.29235/1561-8323-2020-64-5-583-589
Abstract
The article substantiates the mechanisms and significance of the increased contents of blood plasma cholesterol and high density lipoproteins (HDLP) under acute exposure to stress factors leading to activation of metabolism. To a great extent, these changes reflect the adaptation rearrangements in cell membranes that are predominantly haracterized by a decreased content of free cholesterol in their composition due to its efflux to HDLP particles . The changes in HDLP fatty acid composition also contribute to this process resulting in a reduction of membrane microviscosity so that to intensify the intracellular metabolism and to enhance cellular functional activity.
About the Authors
I. N. Semenenya
Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus
Belarus
Belarus
Semenenya Igor N. - D. Sc. (Medicine), Professor, Director, Institute of Biochemistry of Biologically Active Substances of the National Academy of Sciences of Belarus.
50, Leninskogo Komsomola Boulevar, 230030, Grodno.
A. A. Astrouski
Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus
Belarus
Belarus
Astrouski Aliaksandr A. - D. Sc. (Medicine), Professor, Head of the Group. Institute of Biochemistry of Biologically Active Substances of the National Academy of Sciences of Belarus.
50, Leninskogo Komsomola Boulevar, 230030, Grodno.
A. V. Shuriberko
Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus
Belarus
Belarus
Shuriberko Aleksey V. - Head of the Sector, Institute of Biochemistry of Biologically Active Substances of the National Academy of Sciences of Belarus.
50, Leninskogo Komsomola Boulevar, 230030, Grodno.
Yu. E. Razvodovsky
Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus
Belarus
Belarus
Razvodovsky Yuri E. - Head of the Laboratory, Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus.
50, Leninskogo Komsomola Boulevar, 2300030, Grodno.
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